Journal article
Frequency and implications of malnutrition in systemic sclerosis
JL Fairley, D Hansen, A Quinlivan, S Proudman, J Sahhar, GS Ngian, J Walker, LV Host, K Morrisroe, W Stevens, L Ross, M Nikpour
Rheumatology | OXFORD UNIV PRESS | Published : 2025
Open access
Abstract
Objectives: To quantify the frequency and impact of malnutrition in systemic sclerosis (SSc), as diagnosed by the Global Leadership Initiative on Malnutrition (GLIM) criteria, based on weight loss, BMI and muscle atrophy. Methods: Australian Scleroderma Cohort Study participants meeting ACR/EULAR criteria for SSc with ≥1 concurrent weight and height measurement were included. The chi-squared test, two-sample t-test or Wilcoxon’s rank-sum test was used for between-group comparison as appropriate. Multivariable logistic regression models were used to establish the determinants of malnutrition diagnosis. Kaplan–Meier and Cox proportional hazard models were used for survival analyses, based on m..
View full abstractGrants
Awarded by St Vincent's Hospital Melbourne IT Department and Research Endowment Fund (REF)
Awarded by NHMRC Investigator Grant
Funding Acknowledgements
The Australian Scleroderma Cohort Study (ASCS) is supported by Janssen, Boehringer Ingelheim, Scleroderma Australia, Scleroderma Victoria, Arthritis Australia, Musculoskeletal Australia (muscle, bone and joint health), Australian Rheumatology Association and St Vincent's Hospital Melbourne IT Department and Research Endowment Fund (REF). J.L.F. holds a NHMRC Postgraduate Scholarship (GNT2013842) and an Australian Government Research Training Program Scholarship. K.M. holds NHMRC Investigator Grant GTN1197169. M.N. holds an NHMRC Investigator Grant (GNT1176538). L.R. is the recipient of a RACP Australian Rheumatology Association & D.E.V. Starr Research Establishment Fellowship & Melbourne Medical School Strategic Grant for Outstanding Women.